The Buffalo Meat can be obtained by killing and skinning a Buffalo.
Buffalo Meat can be sold in stores for money, though the value of the meat can fluctuate, depending on where and when it is sold. Selling the meat at Manzanita Post or Blackwater will fetch a lower price, while selling it outside of West Elizabeth can be more profitable.
Players should sell this meat in Mexico after achieving the Manifest Destiny achievement to get the highest possible price. The buffalo is the only animal that can be made extinct, so the value of their meat is obviously higher after they are gone. Buffalo can be found in and around the Great Plains.
- Note: prices listed on this page are based upon the player having neutral honor and playing the game on Normal difficulty. If the player has high honor, the selling price will be decreased by 50% everywhere except Thieves' Landing. Low Honor increases selling price by 50% everywhere except Thieves' Landing. While playing the game on Hardcore difficulty, money is more scarce and the base, neutral honor price of each item will be slightly lower.