- Force Diego to leave the train.
- Kill Diego.
After the weapon selection screen, there is no cutscene. The mission begins immediately and Diego's health bar appears at the top of the screen. A soldier mounts a Gatling Gun on the train and begins firing at the player while Diego takes potshots from within an armored train car. Soldiers and cannons on the train also begin firing. Some soldiers will leave the train to fight out in the fields as well.
There are large rocks to hide behind where Red begins, but eventually, these will be destroyed, so the player must make their way towards the train. Diego will take refuge within the armored car and will occasionally open a window to taunt and take potshots at Red. When this happens, throw in a stick of dynamite to force him out.
Once Diego leaves the train, he will begin firing at Red with his rifle, using flares or using the bayonet when close. Attack Diego until his health bar is depleted. The final cutscene will show Diego crawling away on his back, trying to bribe Red in exchange for his life. When he utters the words, "What do you say, partner?", much in the way Griffon sold out Red's father, Red responds by putting him down with a shot to the head.
- Main article: Devils and Angels/dialogues
The mission will fail if:
- The player dies.
- Bounty: General Diego $750
- Showdown Mode stage: The Ranch (Good rating)
- Showdown character: Javier Diego (Excellent rating)