It is the westernmost region of the territory and borders the region of Cholla Springs to the northeast and the region of Río Bravo to the southeast. The San Luis River forms the southern border of the region, separating it from Nuevo Paraíso. Based on the presence of Joshua trees and the rough rocky terrain, Gaptooth Ridge is likely based off the Mojave Desert which occurs in eastern California and Nevada, as well as small parts of Arizona and Utah.
This region's properties of being a hot desert, having an abundance of Joshua trees and numerous rugged rock formations make Gaptooth Ridge resemble real-life Joshua Tree National Park in Southern California and other areas throughout Southern California and Nevada, such as the Mojave Desert.
"Gaptooth" may be a reference to the dental hygiene of the miners who inhabit the region. Many can be seen having "gaps" where they are missing a tooth or two.
North of Tumbleweed below the cliffs, there is a cave that can provide shelter from rain/a thunderstorm
In Red Dead Redemption, Benedict Point is located in Gaptooth Ridge. In Red Dead Redemption 2, it is in Río Bravo instead.