|Hold it right there, outlaw!|
This article is littered with spoilers, so I reckon you might ought'a mosey on down the road if you don't want to read any plot details.
Nothing is known of Manolo's background.
Manolo is encountered during the mission "Lucky in Love", during which he is playing a game of poker with Andreas Müller, Landon Ricketts, and the Stranger. However, Ricketts invites John Marston to join the game, and shortly thereafter, Müller accuses Marston of cheating. Guns are drawn, and the group finds themselves at an impasse.
After Marston kills Müller in a duel, the Stranger takes a nearby woman hostage, and threatens to kill her with a knife. Despite him using the woman as a shield, Marston is able to shoot him in the head. Manolo then attacks Marston and Ricketts along with Selestino Herrada and Rigoberto Artiz.
- Even after his death, he can be seen gambling throughout Mexico.
- He can be found at the Tesoro Azul hideout, serving as a mini-boss, who emerges from a building along with two other banditos after a certain number of enemies die.